Litfulo for Hair Loss: The Breakthrough Treatment Explained
If you find yourself suffering from hair loss, it’s always important to visit a doctor so you can establish the underlying cause of the issue and be better informed on the treatments at your disposal. There are many different ways of treating hair loss, and medication is just one of them.
Within the range of available medication, Litfulo (generic name ritlecitinib) has emerged as an increasingly popular choice for patients. In this article, we’ll be explaining how Lifulo works, who is eligible for using this drug, and how it compares to other options.
Summary
- What is Litfulo?
- Who is Litfulo for?
- Can You Get Litfulo on the NHS?
- Potential Side Effects and What to Look Out For
- How Litfulo Compares to Other Options
- Conclusion
What is Litfulo?
Ritlecitinib, best known under the brand name Litfulo, is a medication designed for patients suffering from alopecia areata. Alopecia areata is an autoimmune condition in which the immune system targets and attacks otherwise healthy hair follicles, causing patchy shedding throughout the scalp and/or elsewhere on the body.
Litfulo works by inhibiting the JAK3 and TEC kinase family, blocking the ATP (adenosine triphosphate) binding site. This both blocks the release of some inflammatory cytokines and reduces the production of others, while also reducing the cytolytic activity of immune cells.
By doing this, the body’s immune response is not halted, but rather managed so that damage to the hair is significantly reduced. Patients can expect to see results within 12-24 weeks. It should be noted that Litfulo is not a cure for alopecia areata, but rather allows patients to manage their symptoms.
Who is Litfulo For?
As stated above, Litfulo is intended for use only by patients suffering from alopecia areata. This is a specific form of hair loss caused by autoimmune disease, and therefore treatment with Litfulo is not recommended for other forms of hair loss.
Litfulo is appropriate for use by both adults and adolescents, with patients aged 12-17 experiencing the same overall results as the rest of the patients tested.
Can You Get Litfulo on the NHS?
If you suffer from alopecia areata and are hoping to receive medication through the NHS, you are in luck. In 2024, Litfulo became the first alopecia areata medication to be covered by the NHS.
This is why we strongly recommend that you have your hair loss assessed by your doctor. By identifying the underlying cause, not only will you be able to establish the most appropriate course of action, you can also learn which treatments are covered by the NHS and thus save yourself a lot of time and money.
Potential Side Effects and What to Look Out For
Naturally, all medications come with some side effects. When taking Litfulo, you might experience the following:
- Headache
- Diarrhea
- Acne
- Rash
- Hives
- Folliculitis
- Fever
- Dizziness
As Litfulo is used to treat an autoimmune disorder, it can lower the immune system’s response to infection. Due to this, doctors request that you be tested for tuberculosis (TB) before treatment begins and that you continue to be screened for TB throughout the duration of your treatment.
How Litfulo Compares to Other Options
As alopecia areata is an autoimmune disorder, hair transplants are not considered a viable option for patients. However, there are other treatments available. Litfulo is often reserved for severe cases of alopecia areata. If your symptoms are not yet severe, you might avail of these alternatives:
- Topical Minoxidil: Minoxidil is available as a topical foam in 2% and 5%. For female patients, only the 2% option is recommended. Minoxidil works by increasing blood flow to the scalp and prolonging the anagen (growth) phase of the hair cycle.
- Topical Immunotherapy: Topical immunotherapy medications such as Dinitrochlorobenzene (DNCB), squaric acid dibutylester (SADBE), and diphencyprone (DPCP) have the best proven results of any alopecia areata treatment, with Diphencyprone boasting a success rate of 88-100% in patients with patchy AA.
- Steroids: Steroids, delievered via injection or topically, are also common treatment options for alopecia areata. Ask your doctor if steroids are a suitable course of treatment for you.
Conclusion: Not an Option for Everyone
While there has been some positive buzz around Litfulo, and for good reason, it is important to remember that it is only an appropriate treatment option for those suffering from severe alopecia areata. If you suffer from any other kind of hair loss, Lifulo is not for you.
But never fear. If you are concerned about your hair loss and wish to get to the root of the issue, we recommend that you speak to your doctor. You can also contact one of our experts today to get a free hair analysis and assess whether you might be a good candidate for a hair transplant.
FAQs
How long does Litfulo take to show results?
Most patients begin to see visible hair regrowth within 12 to 24 weeks of consistent treatment. However, results may vary depending on the severity of the condition and individual response to the medication. It’s important to remain patient and continue taking Litfulo as prescribed by your doctor.
Is Litfulo a permanent cure for alopecia areata?
No, Litfulo is not a cure but a treatment that helps manage the symptoms of alopecia areata. Once treatment stops, there is a chance that hair loss may return. Long-term use or a maintenance plan may be necessary, as advised by your healthcare provider.
Can Litfulo be used in combination with other treatments?
While Litfulo is usually prescribed as a standalone treatment, in some cases it may be used alongside topical treatments or corticosteroids under medical supervision. Combining therapies should always be done under the guidance of a specialist to avoid unwanted interactions or reduced efficacy.
How much does Litfulo cost privately if not covered by the NHS?
The private cost of Litfulo can vary depending on the pharmacy and dosage but typically ranges from £800 to £1,200 per month. Patients are encouraged to check if they’re eligible for NHS coverage to reduce or eliminate these costs.
Is Litfulo safe for long-term use?
Clinical trials have shown that Litfulo is generally safe for long-term use when monitored by a healthcare provider. However, due to its immune-modulating effects, ongoing health checks and infection screenings, such as for TB, are required to ensure continued safety.
Are there any lifestyle changes recommended while on Litfulo?
While no drastic lifestyle changes are required, patients are advised to monitor their overall health closely. It’s recommended to avoid exposure to infections, maintain a healthy diet to support immune function, and attend regular check-ups for blood work and screening.
Can Litfulo be used during pregnancy or breastfeeding?
Litfulo is not currently recommended during pregnancy or breastfeeding due to insufficient safety data. Women who are pregnant, planning to conceive, or breastfeeding should consult their doctor for alternative treatment options.
What happens if you stop taking Litfulo suddenly?
Stopping Litfulo abruptly may lead to a return of symptoms, including renewed hair loss. Always speak with your healthcare provider before making any changes to your treatment plan so they can help manage the transition safely.
How is Litfulo taken – is it a pill or injection?
Litfulo is taken orally in the form of a tablet. It is typically prescribed as a once-daily dose and should be taken at the same time each day, with or without food.
Is Litfulo suitable for all ethnic hair types?
Yes, Litfulo has been shown to be effective across a range of ethnic groups and hair types. However, individual results may vary, so it’s best to discuss your unique hair profile and medical history with your doctor.
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